Pdlim5 - PDZ and LIM domain 5 Gene

Rattus norvegicus

Also known as Enh; Enh1

Gene ID: 64353 | Gene type: protein coding

About Pdlim5

Summary

Enables cytoskeletal protein binding activity; protein N-terminus binding activity; and protein kinase C binding activity. Involved in cell growth involved in cardiac muscle cell development; regulation of dendritic spine morphogenesis; and regulation of synapse assembly. Located in cytosol; membrane; and postsynaptic density. Orthologous to human PDLIM5 (PDZ and LIM domain 5). [provided by Alliance of Genome Resources, Apr 2022]

Pdlim5 Products(1)

mRNA	Protein	Name
NM_053326.1	NP_445778.1	PDZ and LIM domain protein 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables actin binding	IDA IDA: Inferred from direct assay	10833443	RGD
enables actinin binding	IDA IDA: Inferred from direct assay	10833443	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	8940095	RGD
enables protein kinase C binding	IDA IDA: Inferred from direct assay	8940095	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cell growth involved in cardiac muscle cell development	IGI IGI: Inferred from genetic interaction	24743145	RGD
involved in regulation of dendritic spine morphogenesis	IDA IDA: Inferred from direct assay	19900557	RGD
involved in regulation of postsynapse assembly	IDA IDA: Inferred from direct assay	19900557	RGD
involved in regulation of postsynapse assembly	IMP IMP: Inferred from mutant phenotype	19900557	RGD
involved in regulation of synapse assembly	IDA IDA: Inferred from direct assay	19900557	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytosol	IDA IDA: Inferred from direct assay	8940095	RGD
is active in glutamatergic synapse	EXP EXP: Inferred from Experiment	19900557	RGD
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	19900557	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	19900557	RGD
located in membrane	IDA IDA: Inferred from direct assay	8940095	RGD
is active in postsynapse	EXP EXP: Inferred from Experiment	19900557	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	19900557	RGD
located in postsynaptic density	IDA IDA: Inferred from direct assay	19900557	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

PDZ and LIM domain protein 5

enigma homolog

enigma-like PDZ and LIM domains protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10283	PDLIM5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21904	Pdlim5 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pdlim5	NCBI	NCBI:10611

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