CDH22 - cadherin 22 Gene
Also Known as C20orf25; dJ998H6.1
Species: Homo sapiens
About CDH22
This gene has 2 transcripts (splice variants), 197 orthologues and 33 paralogues. Biased expression in brain (RPKM 3.4), skin (RPKM 1.8) and 4 other tissues.
Summary
This gene is a member of the Cadherin superfamily. The gene product is composed of five Cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical Cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008]
CDH22 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_021248.3 | NP_067071.1 | cadherin-22 precursor |
CDH22 Protein Structure
Cadherin: Cadherin domain (71 - 158)
Cadherin: Cadherin domain (174 - 268)
Cadherin: Cadherin domain (282 - 363)
Cadherin: Cadherin domain (402 - 490)
Cadherin: Cadherin domain (503 - 600)
Cadherin_C: Cadherin cytoplasmic region (649 - 818)
- 0
- 200
- 400
- 600
- 828 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cadherin-22 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | CDH22 | VGNC | VGNC:39030 |
| Macaca mulatta | CDH22 | VGNC | VGNC:70940 |
| Mus musculus | CDH22 | MGD | MGI:1341843 |
| Bos taurus | CDH22 | VGNC | VGNC:27100 |
| Felis catus | CDH22 | VGNC | VGNC:60680 |
| Rattus norvegicus | CDH22 | RGD | RGD:2321 |
| Others | CDH22 | NCBI |