ENGASE - endo-beta-N-acetylglucosaminidase Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64772

About ENGASE

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:79,074,824-79,088,599 (from NCBI)

This gene has 10 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in spleen (RPKM 23.3), duodenum (RPKM 12.9) and 24 other tissues.

Summary

This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]

ENGASE Products (5)

mRNA Protein Name
NM_001042573.3 NP_001036038.1 cytosolic endo-beta-N-acetylglucosaminidase isoform 4
NM_001396052.1 NP_001382981.1 cytosolic endo-beta-N-acetylglucosaminidase isoform 1
NM_001396053.1 NP_001382982.1 cytosolic endo-beta-N-acetylglucosaminidase isoform 2
NM_001396054.1 NP_001382983.1 cytosolic endo-beta-N-acetylglucosaminidase isoform 3
NM_001396055.1 NP_001382984.1 cytosolic endo-beta-N-acetylglucosaminidase isoform 5

ENGASE Protein Structure

Glyco_hydro_85

Glyco_hydro_85: Glycosyl hydrolase family 85 (131 - 411)

  • 0
  • 200
  • 400
  • 600
  • 743 a.a.
Protein Preferred Names Protein Names

cytosolic endo-beta-N-acetylglucosaminidase

  • Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase

Related Diseases

Diseases Alias
Ngly1-Deficiency

  • Deficiency Of N-Glycanase 1

  • Ngly1-Cddg

  • Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome

  • Ngly1 Deficiency

  • Congenital Disorder Of Deglycosylation

  • Congenital Disorder Of Glycosylation Type Iv

  • Congenital Disorder Of Deglycosylation

  • Cddg

  • Congenital Disorder Of Glycosylation Type Iv

  • Cdg1v
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70070 Endo-β-N-acetylglucosaminidase (Endo A) Inhibitor / Unkown
HY-P2999 Endo-β-N-acetylglucosaminidase / Unkown
HY-RS04375 ENGASE Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ENGASE VGNC VGNC:40363
Felis catus ENGASE VGNC VGNC:61862
Mus musculus ENGASE MGD MGI:2443788
Macaca mulatta ENGASE VGNC VGNC:72099
Bos taurus ENGASE VGNC VGNC:28493
Rattus norvegicus ENGASE RGD RGD:1310868
Others ENGASE NCBI