SLC26A6 - solute carrier family 26 member 6 Gene

Homo sapiens

Gene ID: 65010 | Gene type: protein coding

About SLC26A6

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:48,625,723-48,635,461 (from NCBI)

This gene has 22 transcripts (splice variants), 354 orthologues and 9 paralogues. Ubiquitous expression in colon (RPKM 11.7), bone marrow (RPKM 8.2) and 25 other tissues.

Summary

This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2013]

SLC26A6 Products(6)

mRNA	Protein	Name
NM_001040454.1	NP_001035544.1	solute carrier family 26 member 6 isoform 4
NM_001281732.2	NP_001268661.1	solute carrier family 26 member 6 isoform 5
NM_001281733.2	NP_001268662.1	solute carrier family 26 member 6 isoform 6
NM_022911.3	NP_075062.2	solute carrier family 26 member 6 isoform 1
NM_134263.3	NP_599025.2	solute carrier family 26 member 6 isoform 2
NM_134426.3	NP_602298.2	solute carrier family 26 member 6 isoform 3

SLC26A6 Protein Structure

Sulfate_transp

STAS

0
200
400
600
759 a.a.

Protein Preferred Names

Protein Names

solute carrier family 26 member 6

anion exchange transporter

Related Diseases

Diseases

Alias

Urolithiasis

Spermatocele

Sialolithiasis

Sialolith	Stone Of Salivary Gland Or Duct
Salivary Gland Calculi	Salivary Gland Stone
Calculus Of Salivary Gland Or Duct	Calculus Of Salivary Gland
Salivary Calculus	Salivary Gland Calculus
Salivary Stone	Salivary Duct Calculi
Sialodocholithiasis

Renal Tuberculosis

Tuberculosis, Renal	Tuberculosis Of Kidney
Tuberculosis Renal

Nephrolithiasis

Kidney Stones	Stone - Kidney/Ureter
Kidney Calculi

Diarrhea 1, Secretory Chloride, Congenital

DIAR1	Chloride Diarrhea, Congenital, Finnish Type
Congenital Secretory Chloride Diarrhea 1	Congenital Chloride Diarrhea Finnish Type
Congenital Chloride Diarrhea	Chloridorrhea, Congenital
Congenital Chloride Diarrhoea Finnish Type	Congenital Chloridorrhea
Congenital Secretory Chloride Diarrhoea 1	Chloridorrhea Congenital
Cld	Diarrhea 1 Secretory Chloride Congenital
Diarrhea, Type 1, Chloride, Secretory, Congenital

Lower Urinary Tract Calculus

Calculus Of Lower Urinary Tract

Motility-Related Diarrhea

Urogenital Tuberculosis

Tuberculosis, Urogenital

Genitourinary Tuberculosis

Bladder Calculus

Urinary Bladder Calculi	Urinary Bladder Stone
Bladder Calculi	Bladder Stone
Urinary Bladder Calculus	Vesical Calculi
Vesical Calculus	Vesicolithiasis
Cystolithiasis	Cystic Calculi
Cystic Calculus

Nephrolithiasis, Calcium Oxalate

Kidney Stones	Calculus Of Kidney
Kidney Calculi	Nephrolithiasis
Renal Calculi	Calcium Oxalate Urolithiasis
CAON	Urolithiasis, Calcium Oxalate
Calcium Oxalate Nephrolithiasis	Kidney Stone
Nephrolith	Renal Calculus
Urinary Stones	Renal Stone
Calculus, Kidney	Calculus, Renal
Renal Lithiasis	Renal Stones
Urolithiasis	Renal Calculus Or Stone
Stone In Kidney	Nephritic Calculus
Multiple Kidney Calculi	Multiple Kidney Calculus
Nephrolithiasis Nos	Pelvic Nephrolithiasis
Pelviolithiasis	Pelvis Nephrolithiasis

Diastrophic Dysplasia

Diastrophic Dwarfism	DTD
Dd	Diastrophic Dysplasia, Broad Bone-Platyspondylic Variant
Dysplasia, Diastrophic	Diastrophic Dysplasia Variant

Hyperoxaluria, Primary, Type Iii

Primary Hyperoxaluria Type 3	HP3
Ph Iii	Primary Hyperoxaluria Type Iii
Hyperoxaluria Primary 3	Hyperoxaluria Non-Hp1/Non-Hp2
Hyperoxaluria Non-Ph I/Ph Ii Form	Hyperoxaluria Primary Type Iii

Inflammatory Diarrhea

Pendred Syndrome

Goiter-Deafness Syndrome	Deafness With Goiter
PDS	Thyroid Dyshormonogenesis 2b
Tdh2b	Autosomal Recessive Sensorineural Hearing Impairment And Goiter
Pendred'S Syndrome	Thyroid Hormonogenesis, Genetic Defect In, 2b
Hypothyroidism, Congenital, Due To Dyshormonogenesis, 2b	Congenital Hypothyroidism Due To Dyshormonogenesis 2b
Genetic Defect In Thyroid Hormonogenesis 2b	Autosomal Recessive Sensorineural Hearing Impairment, Enlarged Vestibular Aqueduct, And Goiter
Goiter-Hearing Loss Syndrome	Goitre-Deafness Syndrome
Goitre Deafness

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Purity	Rare Diseases
HY-154912A	PAT1inh-B01 hydrochloride	≥98.0%	Unkown
HY-154912	PAT1inh-B01	98.32%	Unkown
HY-162033	PAT1inh-A0030	/	Unkown
HY-RS13140	SLC26A6 Human Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SLC26A6	VGNC	VGNC:34781
Rattus norvegicus	SLC26A6	RGD	RGD:1310197
Mus musculus	SLC26A6	MGD	MGI:2159728
Macaca mulatta	SLC26A6	VGNC	VGNC:77483

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