JMJD4 - jumonji domain containing 4 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 65094
About JMJD4
This gene has 5 transcripts (splice variants), 195 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 7.3), adrenal (RPKM 6.8) and 25 other tissues.
Summary
Enables 2-oxoglutarate-dependent dioxygenase activity. Involved in positive regulation of translational termination and protein hydroxylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
JMJD4 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001161465.2 | NP_001154937.2 | 2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 2 |
| NM_023007.3 | NP_075383.3 | 2-oxoglutarate and iron-dependent oxygenase JMJD4 isoform 1 |
JMJD4 Protein Structure
Cupin_8
Cupin_8: Cupin-like domain (88 - 331)
- 0
- 100
- 200
- 300
- 400
- 463 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
2-oxoglutarate and iron-dependent oxygenase JMJD4 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Intracranial Chondrosarcoma |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS07038 | JMJD4 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Felis catus | JMJD4 | VGNC | VGNC:63007 |
| Mus musculus | JMJD4 | MGD | MGI:2144404 |
| Rattus norvegicus | JMJD4 | RGD | RGD:1307186 |
| Bos taurus | JMJD4 | VGNC | VGNC:54440 |
| Canis familiaris | JMJD4 | VGNC | VGNC:42188 |
| Macaca mulatta | JMJD4 | VGNC | VGNC:106393 |
| Others | JMJD4 | NCBI |
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