PHACTR4 - phosphatase and actin regulator 4 Gene
Also Known as PPP1R124
Species: Homo sapiens
About PHACTR4
This gene has 9 transcripts (splice variants), 291 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 8.8), thyroid (RPKM 5.5) and 25 other tissues.
Summary
This gene encodes a member of the Phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein Phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHACTR4 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001048183.3 | NP_001041648.1 | phosphatase and actin regulator 4 isoform 1 |
| NM_001350158.2 | NP_001337087.1 | phosphatase and actin regulator 4 isoform 3 |
| NM_001350159.2 | NP_001337088.1 | phosphatase and actin regulator 4 isoform 3 |
| NM_001350160.2 | NP_001337089.1 | phosphatase and actin regulator 4 isoform 1 |
| NM_001350161.2 | NP_001337090.1 | phosphatase and actin regulator 4 isoform 4 |
| NM_023923.4 | NP_076412.3 | phosphatase and actin regulator 4 isoform 2 |
PHACTR4 Protein Structure
RPEL: RPEL repeat (64 - 88)
RPEL: RPEL repeat (584 - 607)
RPEL: RPEL repeat (622 - 645)
- 0
- 200
- 400
- 600
- 702 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
phosphatase and actin regulator 4 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Hirschsprung Disease 1 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS10405 | PHACTR4 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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