2. Gene
  3. Sdhaf2 - succinate dehydrogenase complex assembly factor 2 Gene

Sdhaf2 - succinate dehydrogenase complex assembly factor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 0610038F07Rik

Gene ID: 66072 | Gene type: protein coding

About Sdhaf2

Summary

Acts upstream of or within negative regulation of canonical Wnt signaling pathway; negative regulation of epithelial to mesenchymal transition; and protein dephosphorylation. Located in mitochondrion. Is expressed in several structures, including early conceptus and oocyte. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SDHAF2 (Succinate Dehydrogenase complex assembly factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Sdhaf2 Products(1)

mRNA Protein Name
NM_025333.4 NP_079609.2 succinate dehydrogenase assembly factor 2, mitochondrial precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
23983127 MGI
acts upstream of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
23983127 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
23983127 MGI
acts upstream of or within negative regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
23983127 MGI
acts upstream of or within protein dephosphorylation IMP
IMP: Inferred from mutant phenotype
23983127 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

succinate dehydrogenase assembly factor 2, mitochondrial

SDH assembly factor 2

succinate dehydrogenase subunit 5, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12592 SDHAF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdhaf2 NCBI NCBI:54949