POLR3D - RNA polymerase III subunit D Gene

Homo sapiens

Also known as C53; RPC4; BN51T; RPC53; TSBN51

Gene ID: 661 | Gene type: protein coding

About POLR3D

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,245,133-22,254,601 (from NCBI)

This gene has 5 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in testis (RPKM 12.6), placenta (RPKM 8.6) and 25 other tissues.

Summary

This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008]

POLR3D Products(1)

mRNA	Protein	Name
NM_001722.3	NP_001713.2	DNA-directed RNA polymerase III subunit RPC4

POLR3D Protein Structure

RNA_pol_Rpc4

0
100
200
300
398 a.a.

Protein Preferred Names

Protein Names

DNA-directed RNA polymerase III subunit RPC4

BN51 (BHK21) temperature sensitivity complementing

Related Diseases

Diseases

Alias

Lipoid Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia	Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency
Congenital Lipoid Adrenal Hyperplasia	Lipoid Cah
Lipoid Adrenal Hyperplasia	Adrenal Hyperplasia 1
Cah	Clah
LCAH	Adrenal Hyperplasia I
Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism	Congenital Adrenal Hyperplasia Lipoid
Adrenal Hyperplasia, Congenital	Congenital Adrenal Hyperplasia, Lipoid
AH1	Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism
Adrenal Hyperplasia Congenital	Hyperplasia, Adrenal, Lipoid, Congenital
Congenital Adrenogenital Disorders Associated With Enzyme Deficiency	Congenital Adrenal Cortical Hyperplasia
Congenital Adrenal Gland Hyperplasia	Congenital Adrenogenital Syndrome
Congenital Hyperadrenocorticism	Congenital Adrenogenitalism
Congenital Female Adrenal Pseudohermaphroditism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10858	POLR3D Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	POLR3D	VGNC	VGNC:76017
Felis catus	POLR3D	VGNC	VGNC:64292
Bos taurus	POLR3D	VGNC	VGNC:33148
Mus musculus	POLR3D	MGD	MGI:1914315
Canis familiaris	POLR3D	VGNC	VGNC:44803
Rattus norvegicus	POLR3D	RGD	RGD:1311816

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