Grina - glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) Gene

Also Known as Lag; Tmbim3; 1110025J15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66168

Summary

Enables transmembrane transporter binding activity. Acts upstream of or within endoplasmic reticulum calcium ion homeostasis and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Located in Golgi apparatus and endoplasmic reticulum. Is expressed in cortical plate and genitourinary system. Orthologous to human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Grina Products (1)

mRNA Protein Name
NM_023168.3 NP_075657.1 protein lifeguard 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmembrane transporter binding IDA
IDA: Inferred from direct assay
22240901 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endoplasmic reticulum calcium ion homeostasis IDA
IDA: Inferred from direct assay
22240901 MGI
acts upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
IDA: Inferred from direct assay
22240901 MGI
acts upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
IGI: Inferred from genetic interaction
22240901 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
22240901 MGI
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
22240901 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein lifeguard 1

  • NMDA receptor glutamate-binding subunit

  • glutamate [NMDA] receptor-associated protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05808 GRINA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grina NCBI NCBI:2907