Nenf - neuron derived neurotrophic factor Gene

Also Known as Spuf; SCIRP10; 1110060M21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66208

Summary

Enables growth factor activity. Involved in negative regulation of appetite. Acts upstream of or within positive regulation of MAPK cascade. Located in endoplasmic reticulum; extracellular space; and mitochondrion. Is expressed in brain; heart; lung; metanephros; and spinal cord. Orthologous to human NENF (neudesin neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]

Nenf Products (1)

mRNA Protein Name
NM_025424.3 NP_079700.1 neudesin precursor
Molecular Function GO Annotation Evidence References Source
enables growth factor activity IDA
IDA: Inferred from direct assay
15605373 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
31536960 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of MAPK cascade IDA
IDA: Inferred from direct assay
15605373 MGI
involved in negative regulation of appetite IDA
IDA: Inferred from direct assay
23576617 MGI
acts upstream of or within positive regulation of MAPK cascade IDA
IDA: Inferred from direct assay
15605373 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
31536960 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
15605373 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
31536960 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neudesin

  • SCIRP10-related protein

  • Spinal cord injury related protein 10

  • secreted protein of unknown function

Orthologs Information

Species Symbol Source ID
Homo sapiens Nenf NCBI NCBI:29937