2. Gene
  3. Mthfd2l - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like Gene

Mthfd2l - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1110019K23Rik; C630010D07Rik

Gene ID: 665563 | Gene type: protein coding

About Mthfd2l

Summary

Predicted to enable methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in 10-formyltetrahydrofolate metabolic process and tetrahydrofolate interconversion. Predicted to act upstream of or within cellular amino acid biosynthetic process; one-carbon metabolic process; and purine nucleotide biosynthetic process. Predicted to be located in mitochondrial inner membrane and mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including central nervous system; future brain; gonad; gut; and retina nuclear layer. Orthologous to human MTHFD2L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like). [provided by Alliance of Genome Resources, Apr 2022]

Mthfd2l Products(1)

mRNA Protein Name
NM_026788.1 NP_081064.1 bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial
Protein Preferred Names Protein Names

bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial

probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2

MTHFD2-like

NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155219 TH9028 Inhibitor / Unkown
HY-RS08777 MTHFD2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-148014 TH7299 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mthfd2l NCBI NCBI:441024