Abi3 - ABI family member 3 Gene

Also Known as NESH; 2210414K06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66610

Summary

Predicted to enable SH3 domain binding activity and identical protein binding activity. Involved in defense response to tumor cell; negative regulation of lamellipodium assembly; and negative regulation of protein localization to plasma membrane. Located in lamellipodium. Part of SCAR complex. Is expressed in several structures, including genitourinary system; gut; heart ventricle; lung; and spleen. Orthologous to human ABI3 (ABI family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abi3 Products (2)

mRNA Protein Name
NM_001163464.1 NP_001156936.1 ABI gene family member 3 isoform 2
NM_025659.4 NP_079935.1 ABI gene family member 3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18480067 MGI
Biological Process GO Annotation Evidence References Source
involved in defense response to tumor cell IDA
IDA: Inferred from direct assay
21223585 MGI
involved in negative regulation of lamellipodium assembly IMP
IMP: Inferred from mutant phenotype
26428302 MGI
involved in negative regulation of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
26428302 MGI
Cellular Component GO Annotation Evidence References Source
part of SCAR complex IDA
IDA: Inferred from direct assay
26428302 MGI
located in lamellipodium IDA
IDA: Inferred from direct assay
18480067 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ABI gene family member 3

  • ABI gene family, member 3

  • new molecule including SH3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00101 ABI3BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00100 ABI3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abi3 NCBI NCBI:51225