2. Gene
  3. Uqcrfs1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 Gene

Uqcrfs1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 4430402G14Rik

Gene ID: 66694 | Gene type: protein coding

About Uqcrfs1

Summary

Predicted to enable oxidoreductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; hemolymphoid system; and liver. Used to study Mitochondrial Metabolism disease. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to several human genes including UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1). [provided by Alliance of Genome Resources, Apr 2022]

Uqcrfs1 Products(1)

mRNA Protein Name
NM_025710.2 NP_079986.1 cytochrome b-c1 complex subunit Rieske, mitochondrial
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21278747 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16120479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit Rieske, mitochondrial

RISP

Rieske protein UQCRFS1

complex III subunit 5

cytochrome b-c1 complex subunit 5

rieske iron-sulfur protein

ubiquinol-cytochrome c reductase iron-sulfur subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15501 UQCRFS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uqcrfs1 NCBI NCBI:7386