Duoxa2 - dual oxidase maturation factor 2 Gene

Also Known as Nip2; 9030623N16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66811

Summary

Predicted to enable enzyme binding activity. Acts upstream of or within hydrogen peroxide metabolic process; regulation of inflammatory response; and regulation of thyroid hormone generation. Predicted to be located in several cellular components, including apical part of cell; cell leading edge; and endoplasmic reticulum. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in thyroid dyshormonogenesis 5. Orthologous to human DUOXA2 (dual oxidase maturation factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Duoxa2 Products (1)

mRNA Protein Name
NM_025777.3 NP_080053.1 dual oxidase maturation factor 2
Biological Process GO Annotation Evidence References Source
acts upstream of or within hydrogen peroxide metabolic process IGI
IGI: Inferred from genetic interaction
23770197 MGI
acts upstream of or within regulation of inflammatory response IGI
IGI: Inferred from genetic interaction
23770197 MGI
acts upstream of or within regulation of thyroid hormone generation IGI
IGI: Inferred from genetic interaction
22301785 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual oxidase maturation factor 2

  • Numb-interacting protein 2

Orthologs Information

Species Symbol Source ID
Homo sapiens Duoxa2 NCBI NCBI:405753