2. Gene
  3. Tmem107 - transmembrane protein 107 Gene

Tmem107 - transmembrane protein 107 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1110004B13Rik; 2810049P21Rik

Gene ID: 66910 | Gene type: protein coding

About Tmem107

Summary

Involved in several processes, including embryonic digit morphogenesis; non-motile cilium assembly; and protein localization to ciliary transition zone. Acts upstream of or within several processes, including craniofacial suture morphogenesis; detection of nodal flow; and roof of mouth development. Located in ciliary transition zone. Is expressed in brain ventricle and choroid plexus; nasal cavity epithelium; node; and pharynx. Human ortholog(s) of this gene implicated in Meckel syndrome 13 and orofaciodigital syndrome XVI. Orthologous to human TMEM107 (transmembrane protein 107). [provided by Alliance of Genome Resources, Apr 2022]

Tmem107 Products(4)

mRNA Protein Name
NM_025838.2 NP_080114.1 transmembrane protein 107 isoform 1
NM_028336.3 NP_082612.2 transmembrane protein 107 isoform 2
NM_025838.2 NP_080114.1 transmembrane protein 107 isoform 1
NM_028336.3 NP_082612.2 transmembrane protein 107 isoform 2
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
31887266 MGI
involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
22698544 MGI
acts upstream of or within cilium organization IMP
IMP: Inferred from mutant phenotype
28954202 MGI
acts upstream of or within craniofacial suture morphogenesis IMP
IMP: Inferred from mutant phenotype
28954202 MGI
acts upstream of or within detection of nodal flow IMP
IMP: Inferred from mutant phenotype
31887266 MGI
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
31887266 MGI
involved in embryonic digit morphogenesis IMP
IMP: Inferred from mutant phenotype
22698544 MGI
involved in neural tube patterning IMP
IMP: Inferred from mutant phenotype
22698544 MGI
involved in non-motile cilium assembly IMP
IMP: Inferred from mutant phenotype
26595381 MGI
involved in protein localization to ciliary transition zone IMP
IMP: Inferred from mutant phenotype
26595381 MGI
acts upstream of or within regulation of gene expression IMP
IMP: Inferred from mutant phenotype
28954202 MGI
acts upstream of or within roof of mouth development IMP
IMP: Inferred from mutant phenotype
28954202 MGI
Cellular Component GO Annotation Evidence Reference Source
located in ciliary transition zone IDA
IDA: Inferred from direct assay
26518474 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transmembrane protein 107

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14648 TMEM107 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tmem107 NCBI NCBI:84314