Trim59 - tripartite motif-containing 59 Gene

Also Known as Mrf1; TSBF1; 2310035M22Rik; 2700022F13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66949

Summary

Enables ubiquitin protein Ligase activity. Involved in innate immune response and negative regulation of viral entry into host cell. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling. Located in endoplasmic reticulum. Is expressed in several structures, including Peyer's patch; genitourinary system; gut; nervous system; and skin. Orthologous to human TRIM59 (tripartite motif containing 59). [provided by Alliance of Genome Resources, Apr 2022]

Trim59 Products (1)

mRNA Protein Name
NM_025863.3 NP_080139.3 tripartite motif-containing protein 59

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22588174 MGI
enables ubiquitin protein ligase activity IDA
IDA: Inferred from direct assay
22588174 MGI
Biological Process GO Annotation Evidence References Source
involved in innate immune response IDA
IDA: Inferred from direct assay
18248090 MGI
acts upstream of or within negative regulation of canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
22588174 MGI
involved in negative regulation of viral entry into host cell IDA
IDA: Inferred from direct assay
18248090 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
22588174 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tripartite motif-containing protein 59

  • RING finger 1

  • RING finger protein 1

  • tumor suppressor TSBF1 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15059 TRIM59 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim59 NCBI NCBI:286827