Bfar - bifunctional apoptosis regulator Gene

Predicted to enable Caspase binding activity; protein-macromolecule adaptor activity; and ubiquitin protein Ligase activity. Predicted to be involved in negative regulation of IRE1-mediated unfolded protein response; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to act upstream of or within negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in female reproductive system and urinary system. Orthologous to human BFAR (bifunctional Apoptosis regulator). [provided by Alliance of Genome Resources, Apr 2022]