Rnf41 - ring finger protein 41 Gene

Also Known as FLRF; Nrdp1; D10Ertd722e; 2210404G21Rik; 4930511A05Rik; 4933415P08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67588

Summary

Enables erythropoietin receptor binding activity and interleukin-3 receptor binding activity. Acts upstream of or within several processes, including negative regulation of mitophagy; positive regulation of DNA-binding transcription factor activity; and regulation of hemopoiesis. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum tubular network. Is expressed in several structures, including central nervous system; dorsal root ganglion; male reproductive system; and urinary system. Orthologous to human RNF41 (ring finger protein 41). [provided by Alliance of Genome Resources, Apr 2022]

Rnf41 Products (2)

mRNA Protein Name
NM_001164237.1 NP_001157709.1 E3 ubiquitin-protein ligase NRDP1
NM_026259.3 NP_080535.2 E3 ubiquitin-protein ligase NRDP1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables erythropoietin receptor binding IDA
IDA: Inferred from direct assay
18495327 MGI
enables interleukin-3 receptor binding IDA
IDA: Inferred from direct assay
18495327 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15314180 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of mitophagy IGI
IGI: Inferred from genetic interaction
24949970 MGI
acts upstream of or within protein polyubiquitination IDA
IDA: Inferred from direct assay
18495327 MGI
acts upstream of or within regulation of lymphocyte differentiation IDA
IDA: Inferred from direct assay
18495327 MGI
acts upstream of or within regulation of myeloid cell differentiation IDA
IDA: Inferred from direct assay
18495327 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase NRDP1

  • RING-type E3 ubiquitin transferase NRDP1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12092 RNF41 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf41 NCBI NCBI:10193