Eml1 - echinoderm microtubule associated protein like 1 Gene

Also Known as EMAP; heco; ELP79; EMAPL; EMAP-1; 1110008N23Rik; A930030P13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68519

Summary

Enables microtubule binding activity. Involved in brain development; mitotic spindle organization; and neuroblast proliferation. Acts upstream of or within hematopoietic progenitor cell differentiation. Located in cytosol. Colocalizes with mitotic spindle midzone and mitotic spindle pole. Is expressed in Sertoli cell; liver; lung; nervous system; and retina. Used to study congenital nervous system abnormality and subcortical band heterotopia. Human ortholog(s) of this gene implicated in subcortical band heterotopia. Orthologous to human EML1 (EMAP like 1). [provided by Alliance of Genome Resources, Apr 2022]

Eml1 Products (11)

mRNA Protein Name
NM_001043335.1 NP_001036800.1 echinoderm microtubule-associated protein-like 1 isoform 1
NM_001043336.2 NP_001036801.1 echinoderm microtubule-associated protein-like 1 isoform 2
NM_001286346.1 NP_001273275.1 echinoderm microtubule-associated protein-like 1 isoform 3
NM_001286347.1 NP_001273276.1 echinoderm microtubule-associated protein-like 1 isoform 4
NM_001364193.1 NP_001351122.1 echinoderm microtubule-associated protein-like 1 isoform 5
NM_001364194.1 NP_001351123.1 echinoderm microtubule-associated protein-like 1 isoform 6
NM_001364195.1 NP_001351124.1 echinoderm microtubule-associated protein-like 1 isoform 7
NM_001364196.1 NP_001351125.1 echinoderm microtubule-associated protein-like 1 isoform 4
NM_001364197.1 NP_001351126.1 echinoderm microtubule-associated protein-like 1 isoform 2
NM_001364198.1 NP_001351127.1 echinoderm microtubule-associated protein-like 1 isoform 8
NM_001364199.1 NP_001351128.1 echinoderm microtubule-associated protein-like 1 isoform 9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
24859200 MGI
Biological Process GO Annotation Evidence References Source
involved in brain development IMP
IMP: Inferred from mutant phenotype
24859200 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: Inferred from genetic interaction
24029230 MGI
involved in microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
24859200 MGI
involved in mitotic spindle organization IMP
IMP: Inferred from mutant phenotype
24859200 MGI
involved in neuroblast proliferation IMP
IMP: Inferred from mutant phenotype
24859200 MGI
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
24859200 MGI
colocalizes with mitotic spindle midzone IMP
IMP: Inferred from mutant phenotype
24859200 MGI
colocalizes with mitotic spindle pole IMP
IMP: Inferred from mutant phenotype
24859200 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

echinoderm microtubule-associated protein-like 1

  • echinoderm microtubule associated protein-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04353 EML1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18238 Eml1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24148 Eml2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24717 Eml1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eml1 NCBI NCBI:2009