Evc2 - EvC ciliary complex subunit 2 Gene

Also Known as Lbn; limbin; 1110017L09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68525

Summary

Involved in smoothened signaling pathway. Located in ciliary membrane and nucleus. Part of plasma membrane protein complex. Is expressed in several structures, including heart; limb bud; oral region epithelium; skeleton; and tooth. Used to study Ellis-Van Creveld syndrome. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Evc2 Products (1)

mRNA Protein Name
NM_145920.3 NP_666032.1 limbin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21356043 MGI
Biological Process GO Annotation Evidence References Source
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
21356043 MGI
Cellular Component GO Annotation Evidence References Source
located in ciliary membrane IDA
IDA: Inferred from direct assay
24582806 MGI
located in cilium IDA
IDA: Inferred from direct assay
21356043 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21356043 MGI
part of plasma membrane protein complex IDA
IDA: Inferred from direct assay
24582806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

limbin

  • Ellis van Creveld syndrome 2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04573 EVC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Evc2 NCBI NCBI:132884