2. Gene
  3. Evc2 - EvC ciliary complex subunit 2 Gene

Evc2 - EvC ciliary complex subunit 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Lbn; limbin; 1110017L09Rik

Gene ID: 68525 | Gene type: protein coding

About Evc2

Summary

Involved in smoothened signaling pathway. Located in ciliary membrane and nucleus. Part of plasma membrane protein complex. Is expressed in several structures, including heart; limb bud; oral region epithelium; skeleton; and tooth. Used to study Ellis-Van Creveld syndrome. Human ortholog(s) of this gene implicated in Ellis-Van Creveld syndrome and Weyers acrofacial dysostosis. Orthologous to human EVC2 (EvC ciliary complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Evc2 Products(1)

mRNA Protein Name
NM_145920.3 NP_666032.1 limbin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
21356043 MGI
Biological Process GO Annotation Evidence Reference Source
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
21356043 MGI
Cellular Component GO Annotation Evidence Reference Source
located in ciliary membrane IDA
IDA: Inferred from direct assay
24582806 MGI
located in cilium IDA
IDA: Inferred from direct assay
21356043 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21356043 MGI
part of plasma membrane protein complex IDA
IDA: Inferred from direct assay
24582806 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

limbin

Ellis van Creveld syndrome 2 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04573 EVC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Evc2 NCBI NCBI:132884