SYT5 - synaptotagmin 5 Gene

Homo sapiens

Gene ID: 6861 | Gene type: protein coding

About SYT5

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:55,171,196-55,180,289 (from NCBI)

This gene has 11 transcripts (splice variants), 102 orthologues and 31 paralogues. Biased expression in brain (RPKM 20.3) and adrenal (RPKM 2.1).

Summary

Synaptotagmins, such as SYT5, are a family of type III membrane proteins characterized by cytoplasmic repeats related to protein kinase C (see MIM 176960) regulatory (C2) domains, which are thought to bind calcium. Synaptotagmins may act both as negative regulators of vesicle fusion, allowing fusion in the presence of calcium, and as calcium receptors or sensor molecules (summary by Hudson and Birnbaum, 1995 [PubMed 7597049]).[supplied by OMIM, Feb 2011]

SYT5 Products(2)

mRNA	Protein	Name
NM_001297774.2	NP_001284703.1	synaptotagmin-5 isoform 2
NM_003180.3	NP_003171.2	synaptotagmin-5 isoform 1

SYT5 Protein Structure

0
100
200
300
386 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-5

synaptotagmin V

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14117	SYT5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SYT5	VGNC	VGNC:35544
Mus musculus	SYT5	MGD	MGI:1926368
Macaca mulatta	SYT5	VGNC	VGNC:78077
Rattus norvegicus	SYT5	RGD	RGD:3806
Felis catus	SYT5	VGNC	VGNC:65900
Canis familiaris	SYT5	VGNC	VGNC:47048