Ppp4r3a - protein phosphatase 4 regulatory subunit 3A Gene

Also Known as Smek1; mKIAA2010; 1110034C04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68734

Summary

Acts upstream of or within positive regulation of gluconeogenesis and protein dephosphorylation. Located in cytoplasm and nucleus. Part of protein Phosphatase 4 complex. Is expressed in several structures, including central nervous system; heart; and retina nuclear layer. Orthologous to human PPP4R3A (protein Phosphatase 4 regulatory subunit 3A). [provided by Alliance of Genome Resources, Apr 2022]

Ppp4r3a Products (4)

mRNA Protein Name
NM_001160214.1 NP_001153686.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 2
NM_211355.2 NP_997594.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1
NM_001160214.1 NP_001153686.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 2
NM_211355.2 NP_997594.1 serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20876121 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of gluconeogenesis IDA
IDA: Inferred from direct assay
20876121 MGI
acts upstream of or within positive regulation of gluconeogenesis IDA
IDA: Inferred from direct assay
20876121 MGI
acts upstream of or within protein dephosphorylation IMP
IMP: Inferred from mutant phenotype
20876121 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
20876121 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20876121 MGI
part of protein phosphatase 4 complex IDA
IDA: Inferred from direct assay
20876121 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 4 regulatory subunit 3A

  • SMEK homolog 1, suppressor of mek1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10998 PPP1R3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11015 PPP2R3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22019 Ppp2r3a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28537 Ppp2r3a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown