Ing2 - inhibitor of growth family, member 2 Gene

Also Known as Ing1l; Ing2b; P33ING2; 2810011M06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69260

Summary

Predicted to enable DNA binding activity; methylated histone binding activity; and phosphatidylinositol binding activity. Involved in several processes, including male gamete generation; positive regulation of histone deacetylation; and seminiferous tubule development. Acts upstream of or within negative regulation of apoptotic signaling pathway and positive regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of CCAAT-binding activity factor complex and Sin3 complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and immune system. Orthologous to human ING2 (inhibitor of growth family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Ing2 Products (1)

mRNA Protein Name
NM_023503.3 NP_075992.2 inhibitor of growth protein 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in flagellated sperm motility IMP
IMP: Inferred from mutant phenotype
21124965 MGI
involved in male germ-line stem cell asymmetric division IMP
IMP: Inferred from mutant phenotype
21124965 MGI
involved in male meiosis I IMP
IMP: Inferred from mutant phenotype
21124965 MGI
acts upstream of or within negative regulation of apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21124965 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16098148 MGI
involved in seminiferous tubule development IMP
IMP: Inferred from mutant phenotype
21124965 MGI
involved in spermatid development IMP
IMP: Inferred from mutant phenotype
21124965 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
21124965 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inhibitor of growth protein 2

  • inhibitor of growth 1-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06808 ING2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06809 ING3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ing2 NCBI NCBI:3622