2. Gene
  3. APC - APC regulator of WNT signaling pathway Gene

APC - APC regulator of WNT signaling pathway Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 693443 | Gene type: protein coding

About APC

Primary_assembly 6: 110,225,908-110,371,282 forward strand.Mmul_10:CM014341.1

This gene has 7 transcripts (splice variants), 169 orthologues and 1 paralogue.

APC Products(15)

mRNA Protein Name
XM_028849655.1 XP_028705488.1 adenomatous polyposis coli protein isoform X8
XM_028849650.1 XP_028705483.1 adenomatous polyposis coli protein isoform X3
XM_028849652.1 XP_028705485.1 adenomatous polyposis coli protein isoform X5
XM_028849651.1 XP_028705484.1 adenomatous polyposis coli protein isoform X3
XM_028849656.1 XP_028705489.1 adenomatous polyposis coli protein isoform X9
XM_028849653.1 XP_028705486.1 adenomatous polyposis coli protein isoform X6
XM_015140578.2 XP_014996064.2 adenomatous polyposis coli protein isoform X6
XM_015140573.2 XP_014996059.2 adenomatous polyposis coli protein isoform X1
XM_015140577.2 XP_014996063.2 adenomatous polyposis coli protein isoform X4
XM_015140582.2 XP_014996068.2 adenomatous polyposis coli protein isoform X10
XM_015140575.2 XP_014996061.2 adenomatous polyposis coli protein isoform X3
XM_028849654.1 XP_028705487.1 adenomatous polyposis coli protein isoform X6
XM_015140581.2 XP_014996067.2 adenomatous polyposis coli protein isoform X7
XM_015140580.2 XP_014996066.2 adenomatous polyposis coli protein isoform X2
XM_015140574.2 XP_014996060.2 adenomatous polyposis coli protein isoform X3

APC Protein Structure

Suppressor_APC

Suppressor_APC: pfam11414 (136 - 216)

ARM

ARM: smart00185 (349 - 401)

APC_rep

APC_rep: pfam18797 (402 - 475)

ARM

ARM: sd00043 (499 - 535)

ARM

ARM: smart00185 (539 - 580)

ARM

ARM: sd00043 (543 - 580)

ARM

ARM: sd00043 (590 - 622)

ARM

ARM: sd00043 (630 - 671)

ARM

ARM: smart00185 (676 - 716)

ARM

ARM: sd00043 (680 - 714)

Arm

Arm: pfam00514 (718 - 758)

ARM

ARM: sd00043 (722 - 758)

Arm_APC_u3

Arm_APC_u3: pfam16629 (759 - 1046)

APC_u5

APC_u5: pfam16630 (1063 - 1162)

APC_r

APC_r: pfam05923 (1284 - 1301)

APC_u9

APC_u9: pfam16633 (1310 - 1395)

APC_r

APC_r: pfam05923 (1398 - 1420)

APC_r

APC_r: pfam05923 (1664 - 1687)

APC_u13

APC_u13: pfam16634 (1689 - 1742)

SAMP

SAMP: pfam05924 (1743 - 1764)

APC_u14

APC_u14: pfam16635 (1773 - 1866)

APC_u15

APC_u15: pfam16636 (1900 - 1974)

SAMP

SAMP: pfam05924 (2061 - 2080)

APC_basic

APC_basic: pfam05956 (2251 - 2596)

EB1_binding

EB1_binding: pfam05937 (2698 - 2870)

  • 0
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  • 2500
  • 2871 a.a.
Protein Preferred Names Protein Names

adenomatous polyposis coli protein

APC, WNT signaling pathway regulator

adenomatosis polyposis coli

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112968 Human protein C / Unkown
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-124955 proTAME Inhibitor 98.20% Unkown
HY-110287 Apcin Inhibitor 99.62% Unkown
HY-13255 TAME Inhibitor 99.51% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-P1918 Activated Protein C (390-404), human 98.74% Unkown
HY-13255A TAME hydrochloride Inhibitor 98.31% Unkown
HY-122142A Pyr-​Pro-​Arg-​pNA hydrochloride Substrate 99.24% Unkown
HY-126016 MAI-400 Inhibitor / Unkown
HY-P1918A Activated Protein C (390-404), human TFA / Unkown
HY-116473 CFM-1 Antagonist / Unkown
HY-112968A Bovine Protein C / Unkown
HY-172401 CDC20-IN-2 Inhibitor / Unkown
HY-122142 Pyr-​Pro-​Arg-​pNA Substrate / Unkown
HY-179012 CDC20/HSP90-IN-1 Inhibitor / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P992193 Anti-B7-H7 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens APC NCBI NCBI:324
Macaca fascicularis APC NCBI NCBI:102126553
Mus musculus APC NCBI NCBI:11789
Susscrofa domestica APC NCBI
Rattus norvegicus APC NCBI NCBI:24205