APC - APC regulator of WNT signaling pathway Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 693443

About APC

Primary_assembly 6: 110,225,908-110,371,282 forward strand.Mmul_10:CM014341.1

This gene has 7 transcripts (splice variants), 169 orthologues and 1 paralogue.

APC Products (15)

mRNA Protein Name
XM_028849655.1 XP_028705488.1 adenomatous polyposis coli protein isoform X8
XM_028849650.1 XP_028705483.1 adenomatous polyposis coli protein isoform X3
XM_028849652.1 XP_028705485.1 adenomatous polyposis coli protein isoform X5
XM_028849651.1 XP_028705484.1 adenomatous polyposis coli protein isoform X3
XM_028849656.1 XP_028705489.1 adenomatous polyposis coli protein isoform X9
XM_028849653.1 XP_028705486.1 adenomatous polyposis coli protein isoform X6
XM_015140578.2 XP_014996064.2 adenomatous polyposis coli protein isoform X6
XM_015140573.2 XP_014996059.2 adenomatous polyposis coli protein isoform X1
XM_015140577.2 XP_014996063.2 adenomatous polyposis coli protein isoform X4
XM_015140582.2 XP_014996068.2 adenomatous polyposis coli protein isoform X10
XM_015140575.2 XP_014996061.2 adenomatous polyposis coli protein isoform X3
XM_028849654.1 XP_028705487.1 adenomatous polyposis coli protein isoform X6
XM_015140581.2 XP_014996067.2 adenomatous polyposis coli protein isoform X7
XM_015140580.2 XP_014996066.2 adenomatous polyposis coli protein isoform X2
XM_015140574.2 XP_014996060.2 adenomatous polyposis coli protein isoform X3

APC Protein Structure

Suppressor_APC

Suppressor_APC: pfam11414 (136 - 216)

ARM

ARM: smart00185 (349 - 401)

APC_rep

APC_rep: pfam18797 (402 - 475)

ARM

ARM: sd00043 (499 - 535)

ARM

ARM: smart00185 (539 - 580)

ARM

ARM: sd00043 (543 - 580)

ARM

ARM: sd00043 (590 - 622)

ARM

ARM: sd00043 (630 - 671)

ARM

ARM: smart00185 (676 - 716)

ARM

ARM: sd00043 (680 - 714)

Arm

Arm: pfam00514 (718 - 758)

ARM

ARM: sd00043 (722 - 758)

Arm_APC_u3

Arm_APC_u3: pfam16629 (759 - 1046)

APC_u5

APC_u5: pfam16630 (1063 - 1162)

APC_r

APC_r: pfam05923 (1284 - 1301)

APC_u9

APC_u9: pfam16633 (1310 - 1395)

APC_r

APC_r: pfam05923 (1398 - 1420)

APC_r

APC_r: pfam05923 (1664 - 1687)

APC_u13

APC_u13: pfam16634 (1689 - 1742)

SAMP

SAMP: pfam05924 (1743 - 1764)

APC_u14

APC_u14: pfam16635 (1773 - 1866)

APC_u15

APC_u15: pfam16636 (1900 - 1974)

SAMP

SAMP: pfam05924 (2061 - 2080)

APC_basic

APC_basic: pfam05956 (2251 - 2596)

EB1_binding

EB1_binding: pfam05937 (2698 - 2870)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2871 a.a.
Protein Preferred Names Protein Names

adenomatous polyposis coli protein

  • APC, WNT signaling pathway regulator

  • adenomatosis polyposis coli

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-112968 Human protein C / Unkown

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124955 proTAME Inhibitor 98.20% Unkown
HY-110287 Apcin Inhibitor 99.62% Unkown
HY-13255 TAME Inhibitor 99.51% Unkown
HY-130841 Apcin-A Inhibitor 98.0% Unkown
HY-P1918 Activated Protein C (390-404), human 98.74% Unkown
HY-13255A TAME hydrochloride Inhibitor 98.31% Unkown
HY-122142A Pyr-​Pro-​Arg-​pNA (hydrochloride) Substrate 99.24% Unkown
HY-182052 Ferroptosis inducer-16 Inhibitor / Unkown
HY-112968A Bovine Protein C / Unkown
HY-122142 Pyr-​Pro-​Arg-​pNA Substrate / Unkown
HY-126016 MAI-400 Inhibitor / Unkown
HY-P1918A Activated Protein C (390-404), human TFA / Unkown
HY-116473 CFM-1 Antagonist / Unkown
HY-179012 CDC20/HSP90-IN-1 Inhibitor / Unkown
HY-172401 CDC20-IN-2 Inhibitor / Unkown
HY-W614725 Apcin-A monohydrochloride Inhibitor / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992193 Anti-B7-H7 Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens APC NCBI NCBI:324