Rfx4 - regulatory factor X, 4 (influences HLA class II expression) Gene

Also Known as NYD-sp10; 4933412G19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71137

Summary

Enables chromatin binding activity. Acts upstream of or within central nervous system development; cilium assembly; and regulation of gene expression. Located in nucleus. Is expressed in several structures, including central nervous system; eye; future brain; genitourinary system; and liver. Orthologous to human RFX4 (regulatory factor X4). [provided by Alliance of Genome Resources, Apr 2022]

Rfx4 Products (2)

mRNA Protein Name
NM_001024918.1 NP_001020089.1 transcription factor RFX4 isoform 1
NM_027689.3 NP_081965.2 transcription factor RFX4 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18218630 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
19887680 MGI
acts upstream of or within negative regulation of smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19887680 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18218630 MGI
acts upstream of or within regulation of protein processing IMP
IMP: Inferred from mutant phenotype
19887680 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18218630 MGI
acts upstream of or within telencephalon development IMP
IMP: Inferred from mutant phenotype
19887680 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
18218630 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor RFX4

  • regulatory factor X 4 protein

  • winged-helix transcription factor RFX4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11882 RFX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rfx4 NCBI NCBI:5992