Ano9 - anoctamin 9 Gene

Also Known as Tp53i5; Tmem16j; Trp53i5; 5430425C04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71345

Summary

Enables phospholipid scramblase activity. Acts upstream of or within calcium activated galactosylceramide scrambling; calcium activated phosphatidylcholine scrambling; and calcium activated phosphatidylserine scrambling. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in gut epithelium; lung epithelium; rib cartilage condensation; and skin. Orthologous to human ANO9 (anoctamin 9). [provided by Alliance of Genome Resources, Apr 2022]

Ano9 Products (1)

mRNA Protein Name
NM_178381.3 NP_848468.2 anoctamin-9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
29604966 MGI
enables channel activity IDA
IDA: Inferred from direct assay
36330924 MGI
NOT enables intracellularly calcium-gated chloride channel activity IDA
IDA: Inferred from direct assay
23532839 MGI
enables phospholipid scramblase activity IDA
IDA: Inferred from direct assay
23532839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within calcium activated galactosylceramide scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within calcium activated phosphatidylcholine scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within calcium activated phosphatidylserine scrambling IDA
IDA: Inferred from direct assay
23532839 MGI
acts upstream of or within establishment of localization in cell IDA
IDA: Inferred from direct assay
23532839 MGI
involved in sensory perception of smell IMP
IMP: Inferred from mutant phenotype
36330924 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
36520003 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
20056604 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
29604966 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

anoctamin-9

  • Trp53 inducible protein 5

  • transformation related protein 53 inducible protein 5

  • transmembrane protein 16J

  • tumor protein p53 inducible protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00749 ANO9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ano9 NCBI NCBI:338440