2. Gene
  3. Myo1e - myosin IE Gene

Myo1e - myosin IE Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as myr 3; myosin-1e; 2310020N23Rik; 9130023P14Rik

Gene ID: 71602 | Gene type: protein coding

About Myo1e

Summary

Predicted to enable several functions, including actin filament binding activity; Calmodulin binding activity; and microfilament motor activity. Involved in glomerular basement membrane development; glomerular filtration; and glomerular visceral epithelial cell development. Acts upstream of or within several processes, including platelet-derived growth factor receptor signaling pathway; post-embryonic hemopoiesis; and vasculogenesis. Located in adherens junction; brush border; and cytoplasm. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 6. Orthologous to human MYO1E (Myosin IE). [provided by Alliance of Genome Resources, Apr 2022]

Myo1e Products(1)

mRNA Protein Name
NM_181072.3 NP_851417.2 unconventional myosin-Ie
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within excretion IMP
IMP: Inferred from mutant phenotype
17143286 MGI
involved in glomerular basement membrane development IMP
IMP: Inferred from mutant phenotype
19005011 MGI
involved in glomerular filtration IMP
IMP: Inferred from mutant phenotype
19005011 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
17143286 MGI
acts upstream of or within in utero embryonic development IMP
IMP: Inferred from mutant phenotype
17143286 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
17143286 MGI
acts upstream of or within platelet-derived growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
17143286 MGI
involved in podocyte development IMP
IMP: Inferred from mutant phenotype
19005011 MGI
acts upstream of or within post-embryonic hemopoiesis IMP
IMP: Inferred from mutant phenotype
17143286 MGI
acts upstream of or within vasculogenesis IMP
IMP: Inferred from mutant phenotype
17143286 MGI
Cellular Component GO Annotation Evidence Reference Source
located in adherens junction IDA
IDA: Inferred from direct assay
19005011 MGI
located in brush border IDA
IDA: Inferred from direct assay
20089841 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
19005011 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

unconventional myosin-Ie

molecular motor

unconventional myosin 1E

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08941 MYO1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21659 Myo1c Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myo1e NCBI NCBI:4643