Shtn1 - shootin 1 Gene

Also Known as Shootin1; mKIAA1598; 4930506M07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71653

Summary

Enables Kinesin binding activity. Involved in several processes, including endoplasmic reticulum polarization; positive regulation of neuron migration; and regulation of establishment of cell polarity. Acts upstream of or within regulation of neuron migration. Located in several cellular components, including axonal growth cone; perikaryon; and perinuclear region of cytoplasm. Part of microtubule associated complex. Is expressed in several structures, including alimentary system; lower urinary tract; nervous system; respiratory system; and sensory organ. Orthologous to human SHTN1 (shootin 1). [provided by Alliance of Genome Resources, Apr 2022]

Shtn1 Products (2)

mRNA Protein Name
NM_001114312.1 NP_001107784.1 shootin-1 isoform 1
NM_175172.4 NP_780381.1 shootin-1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinesin binding IPI
IPI: Inferred from physical interaction
23864681 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
23864681 MGI
Biological Process GO Annotation Evidence References Source
involved in endoplasmic reticulum polarization IMP
IMP: Inferred from mutant phenotype
23864681 MGI
involved in neuron projection morphogenesis IMP
IMP: Inferred from mutant phenotype
23864681 MGI
involved in positive regulation of neuron migration IMP
IMP: Inferred from mutant phenotype
23864681 MGI
acts upstream of or within regulation of establishment of cell polarity IGI
IGI: Inferred from genetic interaction
23864681 MGI
involved in regulation of establishment of cell polarity IMP
IMP: Inferred from mutant phenotype
23864681 MGI
acts upstream of or within regulation of neuron migration IGI
IGI: Inferred from genetic interaction
23864681 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
23864681 MGI
located in axonal growth cone IDA
IDA: Inferred from direct assay
23864681 MGI
located in cell leading edge IDA
IDA: Inferred from direct assay
23864681 MGI
located in growth cone IDA
IDA: Inferred from direct assay
23864681 MGI
part of microtubule associated complex IDA
IDA: Inferred from direct assay
23864681 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
23864681 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
23864681 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
23864681 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

shootin-1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12888 SHTN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shtn1 NCBI NCBI:57698