TPTE - transmembrane phosphatase with tensin homology Gene

Homo sapiens

Also known as CT44; PTEN2

Gene ID: 7179 | Gene type: protein coding

About TPTE

Cytogenetic location: 21p11.2 Genomic coordinates (GRCh38): 21:10,521,583-10,605,716 (from NCBI)

This gene has 5 transcripts (splice variants), 182 orthologues and 6 paralogues. Restricted expression toward testis (RPKM 57.8).

Summary

This gene encodes a PTEN-related tyrosine Phosphatase which may play a role in the signal transduction pathways of the endocrine or spermatogenic function of the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

TPTE Products(4)

mRNA	Protein	Name
NM_001290224.2	NP_001277153.2	putative tyrosine-protein phosphatase TPTE isoform delta
NM_199259.4	NP_954868.2	putative tyrosine-protein phosphatase TPTE isoform beta
NM_199260.4	NP_954869.2	putative tyrosine-protein phosphatase TPTE isoform gamma
NM_199261.4	NP_954870.3	putative tyrosine-protein phosphatase TPTE isoform alpha

TPTE Protein Structure

Ion_trans

DSPc

PTEN_C2

0
100
200
300
400
500
551 a.a.

Protein Preferred Names

Protein Names

putative tyrosine-protein phosphatase TPTE

PTEN-related tyrosine phosphatase

Related Diseases

Diseases

Alias

Brain Glioblastoma Multiforme

Brain Glioblastoma	Glioblastoma Multiforme Of Brain
Glioblastoma Nos

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14957	TPTE Human Pre-designed siRNA Set A		/	Unkown
HY-RS14958	TPTE2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TPTE	MGD	MGI:2446460

Name
Email *

	Sorry, but the email address you supplied was invalid.