2. Gene
  3. Efhc1 - EF-hand domain (C-terminal) containing 1 Gene

Efhc1 - EF-hand domain (C-terminal) containing 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mRib72-1; myoclonin1; 1700029F22Rik

Gene ID: 71877 | Gene type: protein coding

About Efhc1

Summary

Enables protein C-terminus binding activity. Predicted to be involved in several processes, including cerebral cortex cell migration; cilium-dependent cell motility; and mitotic spindle organization. Located in axoneme and neuronal cell body. Is expressed in several structures, including brain; epithelium; future hindbrain roof plate; lung; and spinal cord ventricular layer. Used to study juvenile myoclonic epilepsy. Human ortholog(s) of this gene implicated in juvenile absence epilepsy 1 and juvenile myoclonic epilepsy. Orthologous to human EFHC1 (EF-hand domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Efhc1 Products(1)

mRNA Protein Name
NM_027974.1 NP_082250.1 EF-hand domain-containing protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15258581 MGI
Biological Process GO Annotation Evidence Reference Source
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in axonemal A tubule inner sheath IDA
IDA: Inferred from direct assay
37295417 MGI
located in axoneme IDA
IDA: Inferred from direct assay
15670853 MGI
located in cilium IDA
IDA: Inferred from direct assay
15670853 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15258581 MGI
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EF-hand domain-containing protein 1

myoclonin-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04188 EFHC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efhc1 NCBI NCBI:114327