OPRL1 - opioid related nociceptin receptor 1 Gene

Macaca mulatta

Gene ID: 719224 | Gene type: protein coding

About OPRL1

Primary_assembly 10: 99,318,778-99,328,265 forward strand.Mmul_10:CM014345.1

This gene has 2 transcripts (splice variants), 202 orthologues and 16 paralogues.

Summary

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

OPRL1 Products(2)

mRNA	Protein	Name
NM_001320615.1	NP_001307544.1	nociceptin receptor isoform 1x
NM_001320614.1	NP_001307543.1	nociceptin receptor isoform 1

OPRL1 Protein Structure

7tmA_NOFQ_opioid_R

0
100
200
300
399 a.a.

Protein Preferred Names

Protein Names

nociceptin receptor

Orphanin FQ receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09803	OPRL1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS09804	Oprl1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS09805	Oprl1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	OPRL1	NCBI	NCBI:4987

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