2. Gene
  3. Rnf135 - ring finger protein 135 Gene

Rnf135 - ring finger protein 135 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Riplet; U 2-3-0; 0610037N03Rik; 2410006N06Rik

Gene ID: 71956 | Gene type: protein coding

About Rnf135

Summary

Predicted to enable several functions, including RIG-I binding activity; identical protein binding activity; and ubiquitin protein Ligase activity. Involved in RIG-I signaling pathway; Antiviral innate immune response; and protein polyubiquitination. Predicted to be located in cytoplasmic stress granule. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm. Is expressed in testis. Orthologous to human RNF135 (ring finger protein 135). [provided by Alliance of Genome Resources, Apr 2022]

Rnf135 Products(1)

mRNA Protein Name
NM_028019.4 NP_082295.1 E3 ubiquitin-protein ligase RNF135
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence Reference Source
involved in RIG-I signaling pathway IGI
IGI: Inferred from genetic interaction
21147464 MGI
involved in RIG-I signaling pathway IMP
IMP: Inferred from mutant phenotype
21147464 MGI
involved in antiviral innate immune response IMP
IMP: Inferred from mutant phenotype
21147464 MGI
involved in protein polyubiquitination IGI
IGI: Inferred from genetic interaction
21147464 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF135

RING-type E3 ubiquitin transferase RNF135

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12049 RNF135 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnf135 NCBI NCBI:84282