Nkiras2 - NFKB inhibitor interacting Ras-like protein 2 Gene

Also Known as KBRAS2; 2410003M04Rik; 4930527H08Rik; D630018G21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71966

Summary

Enables GTPase activating protein binding activity. Acts upstream of or within several processes, including Ral protein signal transduction; regulation of signal transduction; and surfactant homeostasis. Predicted to be located in cytoplasm. Is expressed in cerebral cortex; dorsal root ganglion; and nose. Orthologous to human NKIRAS2 (NFKB inhibitor interacting Ras like 2). [provided by Alliance of Genome Resources, Apr 2022]

Nkiras2 Products (1)

mRNA Protein Name
NM_028024.2 NP_082300.1 NF-kappa-B inhibitor-interacting Ras-like protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTPase activating protein binding IPI
IPI: Inferred from physical interaction
25220458 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Ral protein signal transduction IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within inflammatory response IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within inflammatory response IMP
IMP: Inferred from mutant phenotype
25220458 MGI
acts upstream of or within lung alveolus development IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within regulation of canonical NF-kappaB signal transduction IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within regulation of canonical NF-kappaB signal transduction IMP
IMP: Inferred from mutant phenotype
25220458 MGI
acts upstream of or within regulation of tumor necrosis factor-mediated signaling pathway IGI
IGI: Inferred from genetic interaction
25220458 MGI
acts upstream of or within surfactant homeostasis IGI
IGI: Inferred from genetic interaction
25220458 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NF-kappa-B inhibitor-interacting Ras-like protein 2

  • I-kappa-B-interacting Ras-like protein 2

  • kappa B-Ras protein 2

  • kappaB-Ras2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09321 NKIRAS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nkiras2 NCBI NCBI:28511