Dnmbp - dynamin binding protein Gene

Also Known as TUBA; 2410003L07Rik; 2410003M15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71972

Summary

This gene encodes a member of the DBL family of guanine nucleotide exchange factors. The encoded protein has been proposed to regulate the actin Cytoskeleton by specifically activating the Rho-family GTPase Cdc42. An interaction between the encoded protein and a Listeria protein has been shown to mediate Listeria Infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Dnmbp Products (10)

mRNA Protein Name
NM_001306088.2 NP_001293017.1 dynamin-binding protein isoform 2
NM_001403290.1 NP_001390219.1 dynamin-binding protein isoform 3
NM_001403291.1 NP_001390220.1 dynamin-binding protein isoform 3
NM_001403292.1 NP_001390221.1 dynamin-binding protein isoform 4
NM_001403293.1 NP_001390222.1 dynamin-binding protein isoform 5
NM_001403294.1 NP_001390223.1 dynamin-binding protein isoform 6
NM_001403295.1 NP_001390224.1 dynamin-binding protein isoform 7
NM_001403296.1 NP_001390225.1 dynamin-binding protein isoform 2
NM_001403297.1 NP_001390226.1 dynamin-binding protein isoform 8
NM_028029.5 NP_082305.1 dynamin-binding protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
14506234 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14506234 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dynamin-binding protein

  • scaffold protein Tuba

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03907 DNMBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dnmbp NCBI NCBI:23268