Tdrd12 - tudor domain containing 12 Gene

Also Known as ECAT8; repro23; EG434165; G1-476-14; 2410004F06Rik; 2410070K17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71981

Summary

Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Involved in several processes, including gamete generation; gene silencing by RNA; and piRNA metabolic process. Part of PET complex. Is expressed in central nervous system; sensory organ; and testis. Orthologous to human TDRD12 (tudor domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]

Tdrd12 Products (2)

mRNA Protein Name
NM_001368387.1 NP_001355316.1 putative ATP-dependent RNA helicase TDRD12 isoform 2
NM_028034.2 NP_082310.1 putative ATP-dependent RNA helicase TDRD12 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in fertilization IMP
IMP: Inferred from mutant phenotype
24067652 MGI
involved in male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
24067652 MGI
involved in piRNA processing IMP
IMP: Inferred from mutant phenotype
24067652 MGI
involved in retrotransposon silencing by piRNA-directed DNA methylation IMP
IMP: Inferred from mutant phenotype
24067652 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
24067652 MGI
Cellular Component GO Annotation Evidence References Source
part of PET complex IDA
IDA: Inferred from direct assay
26669262 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative ATP-dependent RNA helicase TDRD12

  • ES cell associated transcript 8

  • ES cell-associated transcript 8 protein

  • tudor domain-containing protein 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14335 TDRD12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tdrd12 NCBI NCBI:91646