Esco2 - establishment of sister chromatid cohesion N-acetyltransferase 2 Gene

Also Known as 2410004I17Rik; D030072L07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 71988

Summary

Enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Acts upstream of or within several processes, including double-strand break repair; hematopoietic progenitor cell differentiation; and protein localization to chromatin. Located in chromocenter and chromosome. Is expressed in several structures, including alimentary system; brain; gonad; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Roberts syndrome. Orthologous to human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Esco2 Products (1)

mRNA Protein Name
NM_028039.2 NP_082315.3 N-acetyltransferase ESCO2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables lysine N-acetyltransferase activity, acting on acetyl phosphate as donor IMP
IMP: Inferred from mutant phenotype
22101327 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within chromosome segregation IMP
IMP: Inferred from mutant phenotype
22101327 MGI
acts upstream of or within double-strand break repair IMP
IMP: Inferred from mutant phenotype
22614755 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IGI
IGI: Inferred from genetic interaction
24029230 MGI
acts upstream of or within protein localization to chromatin IMP
IMP: Inferred from mutant phenotype
22101327 MGI
Cellular Component GO Annotation Evidence References Source
located in XY body IDA
IDA: Inferred from direct assay
22699483 MGI
located in chromocenter IDA
IDA: Inferred from direct assay
22101327 MGI
located in pericentric heterochromatin IDA
IDA: Inferred from direct assay
22101327 MGI
located in site of double-strand break IDA
IDA: Inferred from direct assay
22614755 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acetyltransferase ESCO2

  • ECO1 homolog 2

  • establishment of cohesion 1 homolog 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N6896 Isoviolanthin Inhibitor 99.87% Unkown
HY-RS04523 ESCO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Esco2 NCBI NCBI:157570