Cnot2 - CCR4-NOT transcription complex, subunit 2 Gene

Also Known as 2600016M12Rik; 2810470K03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72068

Summary

Predicted to enable transcription corepressor binding activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Involved in regulation of stem cell population maintenance and trophectodermal cell differentiation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of CCR4-NOT core complex. Predicted to be active in P-body. Is expressed in several structures, including 1st branchial arch; brain; genitourinary system; hemolymphoid system gland; and intestine. Orthologous to human CNOT2 (CCR4-NOT transcription complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnot2 Products (12)

mRNA Protein Name
NM_001037846.3 NP_001032935.2 CCR4-NOT transcription complex subunit 2 isoform a
NM_001037847.2 NP_001032936.2 CCR4-NOT transcription complex subunit 2 isoform d
NM_001037848.3 NP_001032937.1 CCR4-NOT transcription complex subunit 2 isoform c
NM_001359247.1 NP_001346176.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359248.1 NP_001346177.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359249.1 NP_001346178.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359250.1 NP_001346179.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359251.1 NP_001346180.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359252.1 NP_001346181.1 CCR4-NOT transcription complex subunit 2 isoform e
NM_001359253.1 NP_001346182.1 CCR4-NOT transcription complex subunit 2 isoform f
NM_001359563.1 NP_001346492.1 CCR4-NOT transcription complex subunit 2 isoform g
NM_028082.2 NP_082358.2 CCR4-NOT transcription complex subunit 2 isoform b

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in regulation of stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
22367759 MGI
involved in trophectodermal cell differentiation IMP
IMP: Inferred from mutant phenotype
22367759 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CCR4-NOT transcription complex subunit 2

  • CCR4-associated factor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02902 CNOT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnot2 NCBI NCBI:4848