Seh1l - SEH1-like (S. cerevisiae Gene

Also Known as Seh1; SEH1A; SEH1B; SEC13L; 2610007A16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72124

Summary

Predicted to enable structural molecule activity. Acts upstream of or within defense response to Gram-positive bacterium. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR2 complex and nuclear pore outer ring. Predicted to colocalize with kinetochore. Orthologous to human SEH1L (SEH1 like nucleoporin). [provided by Alliance of Genome Resources, Apr 2022]

Seh1l Products (3)

mRNA Protein Name
NM_001039088.1 NP_001034177.1 nucleoporin SEH1 isoform a
NM_001360934.1 NP_001347863.1 nucleoporin SEH1 isoform c
NM_028112.2 NP_082388.1 nucleoporin SEH1 isoform b

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytokine production involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
20824097 MGI
acts upstream of or within defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
20824097 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nucleoporin SEH1

  • GATOR complex protein SEH1

  • nup107-160 subcomplex subunit SEH1

  • sec13-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12629 SEH1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Seh1l NCBI NCBI:81929