Chchd4 - coiled-coil-helix-coiled-coil-helix domain containing 4 Gene

Also Known as 2410012P20Rik; 2810014D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72170

Summary

Predicted to enable protein-disulfide reductase activity. Involved in mitochondrial respiratory chain complex assembly. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; mitochondrial DNA repair; and regulation of protein export from nucleus. Located in mitochondrion. Orthologous to human CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Chchd4 Products (1)

mRNA Protein Name
NM_133928.2 NP_598689.1 mitochondrial intermembrane space import and assembly protein 40

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24101517 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within cellular response to oxidative stress IDA
IDA: Inferred from direct assay
24101517 MGI
acts upstream of or within establishment of protein localization to mitochondrion IMP
IMP: Inferred from mutant phenotype
24101517 MGI
acts upstream of or within mitochondrial DNA repair IDA
IDA: Inferred from direct assay
24101517 MGI
involved in mitochondrial respiratory chain complex assembly IMP
IMP: Inferred from mutant phenotype
26004228 MGI
acts upstream of or within positive regulation of cellular respiration IMP
IMP: Inferred from mutant phenotype
24101517 MGI
acts upstream of or within regulation of protein export from nucleus IMP
IMP: Inferred from mutant phenotype
24101517 MGI
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
24101517 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial intermembrane space import and assembly protein 40

  • coiled-coil-helix-coiled-coil-helix domain-containing protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02601 CHCHD4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chchd4 NCBI NCBI:131474