Snx6 - sorting nexin 6 Gene

Also Known as 2010006G21Rik; 2610032J07Rik; 2810425K19Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72183

Summary

Enables type I transforming growth factor beta receptor binding activity. Predicted to be involved in several processes, including cellular response to amyloid-beta; cellular response to epidermal growth factor stimulus; and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to act upstream of or within protein transport. Predicted to be located in early endosome membrane and tubular endosome. Predicted to be part of retromer complex. Predicted to be active in endosome. Orthologous to human SNX6 (sorting nexin 6). [provided by Alliance of Genome Resources, Apr 2022]

Snx6 Products (1)

mRNA Protein Name
NM_026998.3 NP_081274.2 sorting nexin-6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables type I transforming growth factor beta receptor binding IPI
IPI: Inferred from physical interaction
21266196 MGI
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
28134614 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
28134614 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
28134614 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
28134614 MGI
is active in postsynaptic early endosome IDA
IDA: Inferred from direct assay
28134614 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sorting nexin-6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13545 SNX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Snx6 NCBI NCBI:58533