2. Gene
  3. Klhl40 - kelch-like 40 Gene

Klhl40 - kelch-like 40 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Kbtbd5; 2310024D23Rik

Gene ID: 72330 | Gene type: protein coding

About Klhl40

Summary

Involved in myotube differentiation and positive regulation of cellular protein metabolic process. Acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process and negative regulation of protein ubiquitination. Located in A band and I band. Part of Cul3-RING ubiquitin Ligase complex. Is expressed in several structures, including diaphragm; genitourinary system; limb segment; musculature; and paraxial mesenchyme. Used to study nemaline myopathy 8. Human ortholog(s) of this gene implicated in nemaline myopathy 8. Orthologous to human KLHL40 (kelch like family member 40). [provided by Alliance of Genome Resources, Apr 2022]

Klhl40 Products(1)

mRNA Protein Name
NM_028202.3 NP_082478.1 kelch-like protein 40
Protein Preferred Names Protein Names

kelch-like protein 40

kelch repeat and BTB (POZ) domain containing 5

kelch repeat and BTB domain-containing protein 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07368 KLHL40 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klhl40 NCBI NCBI:131377