2. Gene
  3. Amer1 - APC membrane recruitment 1 Gene

Amer1 - APC membrane recruitment 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Wtx; Fam123b; 2810002O09Rik

Gene ID: 72345 | Gene type: protein coding

About Amer1

Summary

Predicted to enable beta-catenin binding activity; beta-catenin destruction complex binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Acts upstream of or within adipose tissue development; bone development; and mesenchymal cell differentiation involved in kidney development. Predicted to be located in nuclear body. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; epithelium; genitourinary system; and sensory organ. Used to study osteopathia striata with cranial sclerosis. Human ortholog(s) of this gene implicated in osteopathia striata with cranial sclerosis. Orthologous to human AMER1 (APC membrane recruitment protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Amer1 Products(1)

mRNA Protein Name
NM_175179.4 NP_780388.2 APC membrane recruitment protein 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within adipose tissue development IMP
IMP: Inferred from mutant phenotype
21571217 MGI
acts upstream of or within bone development IMP
IMP: Inferred from mutant phenotype
21571217 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
21571217 MGI
acts upstream of or within mesenchymal cell differentiation involved in kidney development IMP
IMP: Inferred from mutant phenotype
21571217 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

APC membrane recruitment protein 1

family with sequence similarity 123, member B

protein Fam123b

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00649 AMER1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amer1 NCBI NCBI:139285