1. Gene
  2. Mir329 - microRNA 329 Gene

Mir329 - microRNA 329 Gene

Mus musculus

Also known as Mirn329; mir-329; mmu-mir-329

Gene ID: 723842 | Gene type: ncRNA

About Mir329

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within BMP signaling pathway IDA
IDA: Inferred from direct assay
19520079 MGI
involved in cellular metabolic process IMP
IMP: Inferred from mutant phenotype
25124681 MGI
involved in energy homeostasis IMP
IMP: Inferred from mutant phenotype
25124681 MGI
acts upstream of or within negative regulation of angiogenesis IGI
IGI: Inferred from genetic interaction
23878390 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern