2. Gene
  3. Mir322 - microRNA 322 Gene

Mir322 - microRNA 322 Gene

  • Gene
  • Agent
Mus musculus

Also known as Mirn322; mmu-mir-322

Gene ID: 723907 | Gene type: ncRNA

About Mir322

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to forskolin IEP
IEP: Inferred from expression pattern
21993888 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within sensory perception of sound IEP
IEP: Inferred from expression pattern
23646144 MGI
Cellular Component GO Annotation Evidence Reference Source
part of RISC complex IDA
IDA: Inferred from direct assay
23185045 MGI
located in nucleus IDA
IDA: Inferred from direct assay
22863743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-R03019 mmu-miR-322-5p mimic 95.20% Unkown
HY-R03018 mmu-miR-322-3p mimic 94.98% Unkown
HY-RI03019 mmu-miR-322-5p inhibitor 99.93% Unkown
HY-R03018A mmu-miR-322-3p agomir / Unkown
HY-R03019A mmu-miR-322-5p agomir / Unkown
HY-R04347 rno-miR-322-3p mimic / Unkown
HY-R04347A rno-miR-322-3p agomir / Unkown
HY-RI03018 mmu-miR-322-3p inhibitor / Unkown
HY-RI03018A mmu-miR-322-3p antagomir / Unkown
HY-RI03019A mmu-miR-322-5p antagomir / Unkown
HY-RI04347 rno-miR-322-3p inhibitor / Unkown
HY-RI04347A rno-miR-322-3p antagomir / Unkown