Shisa9 - shisa family member 9 Gene

Also Known as Ckamp44; 2700045P11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72555

Summary

Enables PDZ domain binding activity. Involved in regulation of AMPA Receptor activity; regulation of postsynaptic neurotransmitter receptor activity; and regulation of short-term neuronal synaptic plasticity. Located in glutamatergic synapse; postsynaptic density; and synaptic membrane. Part of AMPA glutamate receptor complex. Is integral component of postsynaptic density membrane. Is expressed in brain. Orthologous to human SHISA9 (shisa family member 9). [provided by Alliance of Genome Resources, Apr 2022]

Shisa9 Products (2)

mRNA Protein Name
NM_001174086.1 NP_001167557.1 protein shisa-9 isoform 2 precursor
NM_028277.2 NP_082553.2 protein shisa-9 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
24498314 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within regulation of AMPA receptor activity IMP
IMP: Inferred from mutant phenotype
24498314 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IDA
IDA: Inferred from direct assay
20185686 MGI
involved in regulation of postsynaptic neurotransmitter receptor activity IMP
IMP: Inferred from mutant phenotype
20185686 MGI
involved in regulation of short-term neuronal synaptic plasticity IDA
IDA: Inferred from direct assay
20185686 MGI
Cellular Component GO Annotation Evidence References Source
part of AMPA glutamate receptor complex IDA
IDA: Inferred from direct assay
22632720 MGI
located in dendritic spine membrane IDA
IDA: Inferred from direct assay
20185686 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
20185686 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
20185686 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
20185686 MGI
part of ionotropic glutamate receptor complex IDA
IDA: Inferred from direct assay
20185686 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
20185686 MGI
is active in postsynaptic density membrane IEP
IEP: Inferred from expression pattern
20185686 MGI
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
20185686 MGI
located in synapse IDA
IDA: Inferred from direct assay
20185686 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein shisa-9

  • cystine-knot AMPAR modulating protein of 44 kDa

  • shisa homolog 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12871 SHISA9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shisa9 NCBI NCBI:729993