Prdm4 - PR domain containing 4 Gene
Also Known as SC1; SC-1; 1700031E19Rik; 2810470D21Rik
Species: Mus musculus
Summary
This gene encodes a member of the PR/SET family of zinc finger proteins. This protein has been shown to bind DNA in a sequence-specific manner and has been implicated in neural stem cell proliferation and differentiation. Pseudogenes have been identified on chromosomes 14 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Prdm4 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001302886.1 | NP_001289815.1 | PR domain zinc finger protein 4 isoform 2 |
| NM_001302887.1 | NP_001289816.1 | PR domain zinc finger protein 4 isoform 3 |
| NM_181650.3 | NP_857633.2 | PR domain zinc finger protein 4 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables DNA-binding transcription activator activity, RNA polymerase II-specific |
IMP
IMP: Inferred from mutant phenotype
|
23918801 | MGI |
| enables RNA polymerase II cis-regulatory region sequence-specific DNA binding |
IMP
IMP: Inferred from mutant phenotype
|
23918801 | MGI |
| enables histone methyltransferase binding |
IPI
IPI: Inferred from physical interaction
|
23048031 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of transcription by RNA polymerase II |
IMP
IMP: Inferred from mutant phenotype
|
23918801 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
23048031 | MGI |
| part of histone methyltransferase complex |
IPI
IPI: Inferred from physical interaction
|
23048031 | MGI |
| located in nucleus |
IDA
IDA: Inferred from direct assay
|
23048031 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
PR domain zinc finger protein 4 |
|