2. Gene
  3. Ppp2r2b - protein phosphatase 2, regulatory subunit B, beta Gene

Ppp2r2b - protein phosphatase 2, regulatory subunit B, beta Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SCA12; PR55-BETA; PP2A-PR55B; 2900026H06Rik; 6330404L05Rik; E130009M08Rik

Gene ID: 72930 | Gene type: protein coding

About Ppp2r2b

Summary

Predicted to enable protein Phosphatase regulator activity. Predicted to be involved in several processes, including mitochondrion organization; peptidyl-serine dephosphorylation; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in mitochondrial outer membrane. Predicted to be part of protein Phosphatase type 2A complex. Predicted to be active in cytosol. Predicted to colocalize with Cytoskeleton. Is expressed in several structures, including cranial ganglion; lung; sensory organ; tongue; and viscerocranium. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein Phosphatase 2 regulatory subunit Bbeta). [provided by Alliance of Genome Resources, Apr 2022]

Ppp2r2b Products(3)

mRNA Protein Name
NM_001403965.1 NP_001390894.1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform 3
NM_027531.2 NP_081807.1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform 1
NM_028392.4 NP_082668.1 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform 2
Protein Preferred Names Protein Names

serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11012 PPP2R2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp2r2b NCBI NCBI:5521