Hspb11 - heat shock protein family B (small), member 11 Gene

Also Known as PP25; IFT25; 2900042B11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72938

Summary

Predicted to enable metal ion binding activity. Involved in kidney development; smoothened signaling pathway; and spermatogenesis. Acts upstream of or within animal organ development; left/right axis specification; and skeletal system development. Located in centrosome and cilium. Part of intraciliary transport particle B. Is expressed in germ cell of ovary. Orthologous to human HSPB11 (heat shock protein family B (small) member 11). [provided by Alliance of Genome Resources, Apr 2022]

Hspb11 Products (3)

mRNA Protein Name
NM_001355459.1 NP_001342388.1 intraflagellar transport protein 25 homolog
NM_001355460.1 NP_001342389.1 intraflagellar transport protein 25 homolog
NM_028394.3 NP_082670.1 intraflagellar transport protein 25 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28430876 MGI
Biological Process GO Annotation Evidence References Source
NOT involved in cilium assembly IMP
IMP: Inferred from mutant phenotype
22595669 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
22595669 MGI
involved in kidney development IMP
IMP: Inferred from mutant phenotype
29626631 MGI
acts upstream of or within left/right axis specification IMP
IMP: Inferred from mutant phenotype
22595669 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
22595669 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
22595669 MGI
involved in smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
22595669 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
28430876 MGI
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
19253336 MGI
located in cilium IDA
IDA: Inferred from direct assay
19253336 MGI
part of intraciliary transport particle B IDA
IDA: Inferred from direct assay
19253336 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intraflagellar transport protein 25 homolog

  • heat shock protein beta-11

  • placental protein 25 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06603 IFT25 Human Pre-designed siRNA Set A Pre-designed Set / Unkown