Tymp - thymidine phosphorylase Gene

Also Known as TP; Ecgf1; PDECGF; Pdgfec; PD-ECGF; 2900072D10Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 72962

Summary

Enables thymidine Phosphorylase activity. Involved in dTMP catabolic process. Predicted to be active in cytosol. Is expressed in alimentary system; axial skeleton; central nervous system; hindlimb; and retina. Used to study mitochondrial DNA depletion syndrome 1. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; mitochondrial DNA depletion syndrome 1; mitochondrial encephalomyopathy; pancreatic cancer; and transitional cell carcinoma. Orthologous to human TYMP (thymidine Phosphorylase). [provided by Alliance of Genome Resources, Apr 2022]

Tymp Products (1)

mRNA Protein Name
NM_138302.3 NP_612175.1 thymidine phosphorylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables thymidine phosphorylase activity IMP
IMP: Inferred from mutant phenotype
12077348 MGI
Biological Process GO Annotation Evidence References Source
involved in dTMP catabolic process IMP
IMP: Inferred from mutant phenotype
12077348 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thymidine phosphorylase

  • endothelial cell growth factor 1 (platelet-derived)

  • gliostatin

  • platelet derived growth factor, endothelial cell

  • tdRPase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12557 SCO2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15303 TYMP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tymp NCBI NCBI:1890