Rflna - refilin A Gene

Also Known as cfm; cfm2; Fam101a; 3110032G18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 73121

Summary

Enables filamin binding activity. Acts upstream of or within several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Located in actin filament bundle. Is expressed in several structures, including alimentary system; respiratory system; sensory organ; skeleton; and unsegmented mesenchyme. Orthologous to human RFLNA (refilin A). [provided by Alliance of Genome Resources, Apr 2022]

Rflna Products (1)

mRNA Protein Name
NM_028443.3 NP_082719.1 refilin-A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables filamin binding IDA
IDA: Inferred from direct assay
24436304 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament bundle organization IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within negative regulation of bone mineralization involved in bone maturation IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within negative regulation of chondrocyte development IGI
IGI: Inferred from genetic interaction
24436304 MGI
acts upstream of or within skeletal system morphogenesis IGI
IGI: Inferred from genetic interaction
24436304 MGI
Cellular Component GO Annotation Evidence References Source
located in actin filament bundle IDA
IDA: Inferred from direct assay
24436304 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

refilin-A

  • family with sequence similarity 101, member A

  • filamin-interacting protein FAM101A

  • protein FAM101A

  • refilinA

  • regulator of filamin protein A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11873 RFLNA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rflna NCBI NCBI:144347